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In 2022, just over 7 million prescriptions for GLP-1s were written for adults without diabetes, up from 1.3 million in 2019

248 miR-185-5p overexpression in db/db mice that represent genetic diabetes models leads to alleviated blood hyperglycemia and decreased gluconeogenesis by directly targeting glucose-6-phosphatase (G6Pase)

Kidney protection: Slowed progression of diabetic kidney disease

However, gastrointestinal side effects and loss of lean mass are notable concerns ( Lifestyle interventions, including exercise and dietary modification, remain the cornerstone of obesity and diabetes management, with proven benefits for weight loss, glycemic control, cardiovascular health, and quality of life (30)