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It is free of sugar, gluten, talc, preservatives, and gelatin.

Unreconstituted lyophilized powder stores well at room temperature away from light and heat

In a multicenter study of 146 patients with painful DPN for 1 to 5 years and a pain score of 40 mm on the Short-Form McGill Pain Questionnaire or an ADP score of 4 on an 11-point pain numerical rating scale (NRS), pregabalin significantly reduced the mean pain score compared with placebo (pregabalin, from 6.5 to 4.0

The MTHFR enzyme also converts one form of folate (5,10-methylenetetrahydrofolate) into the active form called 5-methyltetrahydrofolate so the body can use it