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Two families, two receptors, a complete map GHRH analogs and GHRPs are not interchangeable: they target two distinct receptors, activate two parallel cascades, and produce two complementary pharmacological profiles

(PubMed) Rochette L, Ghibu S, Richard C, Zeller M, Cottin Y, Vergely C

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Dose-Dependent Efficacy and Safety of Tirzepatide for Weight Loss in Non-diabetic Adults With Obesity: A Systematic Review and Meta-analysis of Randomized Controlled Trials