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NCT05520775: Semaglutide for Alcohol Use Disorder Status: Underway This is an early-Phase II human trial using a randomized, placebo-controlled, dose-ranging design to investigate the effects of semaglutide, a GLP-1 receptor agonist, on alcohol-related outcomes in adults with alcohol use disorder

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Generally, hydrophilic peptides dissolve well in water or saline, while hydrophobic peptides may require initial dissolution in a small amount of organic solvent (like DMSO or acetic acid) followed by dilution with aqueous buffer