Prevent Muscle and Bone Loss Regular strengthening exercises like lifting weights or using resistance bands are key to combatting this problem, says Stephen Finney, MD, an obesity medicine physician in Dartmouth, Massachusetts, and a diplomate of the American Board of Obesity Medicine
This gap between what patients are self-reporting online and what gets captured in trials is really what motivated this whole line of work, he added
Gastrointestinal side effects such as nausea are typically most pronounced during the first few weeks and following dose increases, generally improving as your body adapts to the medication over 12 weeks
Subsequently, in the large randomised placebo-controlled FIDELIO-DKD trial including adults with type 2 diabetes and CKD, finerenone reduced the risk of the primary kidney outcome (a composite of kidney failure, sustained eGFR decline 40% or kidney death) by ~20% [69]