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PMC 18523

Overall, the dynamics observed for the NAPstars were minor as compared to the response of Peredox, confirming the respective specificity of the two sensors for NADP and NAD redox status in the plant cytosol and validating previous indications from subcellular fractionation measurements that only minor NADP redox changes occur in the cytosol at the onset of illumination 36,37,38

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Establishment of normal concentrations of NAD and Glutathione forms in Whole Blood Next, we applied our profiling methodology to define human population values of the six redox metabolites using frozen whole blood samples from 299 anonymous healthy donors (191 females and 108 males, aged 18-70 years) provided by the Finnish Blood Service BioBank and 38 healthy in-house volunteers