once-weekly semaglutide in adults with alcohol use disorder Semaglutide and Alcohol: What's Safe

Benefits: Proven to help with weight loss Lowers blood sugar levels Can reduce cardiovascular risk in some patients Considerations: Prescription required only available through a healthcare provider Potential side effects nausea, digestive discomfort, and more Cost expensive without insurance coverage Long-term use stopping the drug may lead to weight regain How It Works: LifeVantages MindBody GLP-1 System is a supplement-based approach designed to naturally support GLP-1 activation without pharmaceutical drugs

It found a lack of clinical and nonclinical safety information, and was "particularly concerned" about the absence of any human data by any route, including no data to assess immunogenicity or aggregation

2025 (Online ahead of print)

In their discussion section, they really go for the gold: These data, representing the longest clinical trial of the effects of semaglutide versus placebo on weight, establish the safety and durability of semaglutide effects on weight loss and maintenance in a geographically and racially diverse population of adult men and women with overweight and obesity but not diabetes