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You'll probably feel the hydration effects first - that dizzy, lightheaded feeling starts to fade as your blood pressure stabilizes

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Its phase IIb studies (NCT02706873, NCT02706951) demonstrated that among patients with moderatetosevere RA who had an insufficient response to methotrexate (MTX) or antiTNF therapy, the treatment groups achieved significantly higher ACR 20/50/70 response rates and more substantial improvements in DAS28CRP scores compared to the placebo group, with a rapid onset of efficacy [404]