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Figure 1 SAMe serves mainly as a methyl donor in the cell and transfers its methyl group to substrates such as nucleic acids, proteins, lipids, and secondary metabolites with the formation of S-adenosylhomocysteine (SAH, which is also abbreviated as AdoHcy), via transmethylation (3, 4)

Although it has been known for some time that GSH is important in these processes, the distinct role it plays at each step is still being elucidated

Ramirez, A

Analyses of data on metabolite concentrations and enzyme activities were performed using the JMP 15 Pro software (Cary, NC, USA) for one-way analysis of variance