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Characterization of EGR-1 Expression in the Auditory Cortex Following Kanamycin-Induced Hearing Loss in Mice

About this article Cite this article Mohammad, A., Laboulaye, M.A., Shenhar, C

It plays a crucial role in cellular events such as inflammatory responses, altered cell growth, and apoptosis ( Figure 1 ) ( Figure 1 The role of alterations in the antioxidant system in the pathogenesis of vitiligo has been extensively studied ( CAT gene and reduced catalase activity have also been associated with several metabolic diseases, such as diabetes, hypertension, and peroxisomal/peroxisomal diseases ( On the other hand, the chronic OS will produce an excessive accumulation of ROS, which in turn induces the production of damage-associated molecular patterns (DAMPs) and the release of melanosomal antigens that activate innate immunity ( + T cells are activated through HSP70i activation and antigen presentation by mature dendritic cells ( + T cells are recruited to induce melanocyte apoptosis ( + T cells ( These findings suggest that oxidative stress plays a vital role in the pathogenesis of vitiligo

And dont underappreciate the importance of this process