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Early data showed promising efficacy in non-diabetic obese patients comparable to Lillys Orforglipron with a downward trend in weight loss, although the effect size was less than that of Orforglipron in diabetes subgroup

16S rRNA sequencing In 16S rRNA gene sequencing, the sequences were output from 16S rRNA variable region V3-V4 through Illumina Miseq sequencing platform and demultiplexed by Illumina CAVASA 1.8 that obtained from Biotools Co., Ltd

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