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Zhou J, Wang X, Pineyro MA et al

The active constituent silymarin has anti-inflammatory and antioxidant activity

In 2025, it has rapidly become one of the most talked-about doctor-supervised weight loss programs in the United States

However, current evidence predominantly derives from animal models and in vitro systems, underscoring the need for large-scale, multicenter clinical trials in high-altitude populations to validate drug-microbiome interactions