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The bioactivity of scExe4 was evaluated through measuring GSIS using pancreatic iGL cells, which release Gaussia luciferase-fused insulin in response to high glucose levels 21

Unlike other medications utilized in the management of diabetes, but like the information on SGLT2 inhibitors, there is little evidence on the association of that pharmacologic group with gastrointestinal symptomatology.42 Sodium-glucose cotransporter type 2 inhibitors Sodium-glucose cotransporter type 1 (SGLT1) and type 2 (SGLT2) are members of the SLC5 gene family, a subdivision of a superfamily of sodium cotransporters

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