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However, since they are no longer employed as antisyphilitic agents, their medical use is now principally of historical interest

Our studies also showed a decrease in nitric oxide-mediated responses in aortic rings from GPx1 +/ or GPx1 / mice characterized by decreased accumulation of aortic cGMP following bradykinin treatment

It acts as a selective agonist at the ghrelin receptor (growth hormone secretagogue receptor type 1a, GHS-R1a), the same receptor targeted by the endogenous hormone ghrelin, to stimulate the release of growth hormone (GH) from the anterior pituitary in preclinical models

Chavez-Talavera, O., Tailleux, A., Lefebvre, P