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Benefit #3: Improved Insulin Sensitivity (Strong Evidence) Evidence Quality: Multiple animal studies with human relevance Mechanism: Enhanced glucose metabolism through NAD+ restoration 5-Amino-1MQ significantly improves insulin sensitivity through metabolic optimization

4.2 Natural products enhance antitumor immunotherapy Accumulating evidence indicates that natural products exert multifaceted immunomodulatory effects within the TME, thereby enhancing antitumor immunity and improving the efficacy of cancer immunotherapies (137)

neurodegenerative diseases, such as Alzheimer's or Parkinson's

And if someone eventually raises the dose out of frustration with slow progress, side effects can still appear later