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Potential Side Effects: Mood changes Headache Migraine Fatigue Dizziness Thrombosis Hypertension Nausea Abdominal pain Hepatic impairment Suppressed lactation Absence of periods Increased weight Osteoporosis Acne Alopecia Anemia Risk of developing meningioma Return to Fertility: Ovulation may take 618 months to resume after stopping Depo-Provera

The effectiveness can vary based on factors such as lifestyle, diet, and existing health conditions