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Description

e , NCI-H716 cells were treated with GPCR antagonists (10 M) or vehicle (DMSO) for 15 min before P9 treatment (50 g ml 1 ), then incubated for an additional 2 h, after which GLP-1 secretion was analyzed (n = 6 per group)

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This was a landmark moment because it represented global recognition of GLP-1 medications as a legitimate long-term treatment for obesity rather than a temporary or supplementary intervention