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Description

In parallel with the human studies, preclinical and in vitro pharmacological work has played a crucial role in understanding of the physiological and pathophysiological role of endogenous GIP and the potential of GIP receptor antagonism as a therapeutic concept

Preconception considerations with GLP-1 receptor agonists

However, this is a workaround for a pathological condition, not an optimal protocol

Similarly, loss of GPX-1 or GPX-5 led to increased BODIPY staining, and treatment with ML162 or Fer-1 enhanced or diminished BODIPY intensity in gpx-5 mutants respectively (Fig