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[7] Although a prospective cohort study of middle-aged women indicated that some flavonoid-rich foods are associated with a reduction in all-cause mortality, frequent grapefruit consumption was associated with a small increase in all-cause mortality, possibly because of the clinically significant drug interactions of the non-flavonoid components

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However, neither our AP-day nor AP-life drug exposure measures contributed to the phase-related reduction in dACC glutamate in our mediation analysis (Fig

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