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Prescriptions are filled through Ro's pharmacy partners, typically within days

But it is changing unevenly, and without deliberate policy intervention, the GLP-1 revolution risks becoming one of the starkest examples in modern medicine of a breakthrough that transformed outcomes for those who could afford it, and passed everyone else by.

The second approved indication is for chronic weight management in adults with obesity (BMI 30 kg/m) or those who are overweight (BMI 27 kg/m) with at least one weight-related comorbidity, such as hypertension, dyslipidaemia, or obstructive sleep apnoea

For patients meeting NICE criteria for weight management therapy (BMI 35 kg/m with adjustment for ethnicity, presence of weight-related comorbidities, and treatment through specialist weight management services), the dual benefit of weight reduction and blood pressure lowering may be particularly valuable