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Resveratrol added to the culture medium during in vitro cultivation of oocytes increased blastocyst formation, reduced OS of vitrified mice oocytes, and improved oocyte maturation and embryo development [141]

Therefore, restoration of gene pattern characteristic of healthy stem cells, which leads to activation of integrins and p63 cellular pathways may be another target of GHK's gene modulatory activity relevant to skin regeneration [28, 29]