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The National Institute for Health and Care and Excellence (NICE) has recommended the use of semaglutide for a maximum of 2 years alongside a reduced-calorie diet and increased physical activity to adults who have: at least 1 weight-related comorbidity and: a body mass index (BMI) of at least 35.0 kg/m2, or a BMI of 30.0 kg/m2 to 34.9 kg/m2 and meet the criteria for referral to specialist weight management services