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Going beyond 2026, the first European countries will make up the second wave of markets to lose exclusivity, starting with the Baltics and parts of Central and Eastern Europe
While no direct comparison between retatrutide and tirzepatide is available and duration of use is different (36- 48 weeks with retatrutide versus 72 weeks with tirzepatide), retatrutide may be superior to tirzepatide in both parameters, particularly weight loss (Table 2) [3,4,10,11]
greener peptide synthesis, oral formulations), strategic partnerships with CDMOs, and workforce development will shape how well the industry meets the booming demand