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A novel mechanism of gamma-aminobutyric acid (GABA) protecting human umbilical vein endothelial cells (HUVECs) against H2O2-induced oxidative injury

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Among these receptors, NLRP3 plays a central role in sensing cellular stress and danger signals

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Mechanistically, MT1G exerts a negative regulatory effect on NF-B signaling and facilitates the degradation of the NF-B p65 subunit by upregulating the expression of E3 ligase TRAF7, consequently suppressing PDAC stemness

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