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It requires professional cosmetic treatments or targeted medical guidance to treat the root cause of melasma

Thus, increased Nrf2 activity does not initiate cancer development but confers advantages in terms of proliferation and stress resistance once a cell acquires uncontrolled proliferative properties

[13] Important interactions may occur with: Diabetes medications (potentially causing hypoglycaemia) Anticoagulants like warfarin and direct oral anticoagulants (DOACs) Immunosuppressants such as ciclosporin and tacrolimus Certain statins and antiarrhythmic medications Antihypertensives and other cardiovascular drugs If you are taking any prescription medications, consult your GP or pharmacist before starting berberine

PMC 11745855