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cAMP accumulation assay CHOFlpIn WT GLP-1R or CHOFlpIn mutant GLP-1R cells were seeded at a density of 30,000 cells per well into a 96-well plate and incubated overnight at 37 C in 5% CO 2

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Tesamorelin is a 44-amino acid peptide and should be protected from repeated freeze-thaw cycles once reconstituted

Patients treated with a lower 9-mg dose shed 26.4%, or 64.2 pounds, of their body weight