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The culture medium consisted of 10% fetal bovine serum, 1% penicillin/streptomycin, 2% Ultroser G (Pall Corp.), and 1% ITS Plus (Zen-Bio) to support optimal cell growth

doi: 10.1016/j.bbr.2020.112947 34 DinizCRAFCasarottoPCFredSMBiojoneCCastrnEJocaSRL

Thoughtful consideration of selection of initial therapy, management of drug dosing, and use of adjunctive therapies throughout the course of PD is necessary to optimize long-term therapeutic outcomes and minimize adverse effects