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Participants treated with liraglutide (239), semaglutide (240), or tirzepatide (200) in the clinical trials had a percent reduction in fat mass approximately three times greater than the reduction in lean mass, leading to an overall improvement in body composition

The Carnipure certified brand is a pure crystalline form of branded L-carnitine, which is valued for its exceptional purity and quality

Comment: A commenter recommended that CMS consider a composite adherence measure or a PRO-PM linked measure to better capture the value of guideline-directed medical therapy in practice

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