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For people with absorption issues (and most adults over 50 have at least some), oral B12 simply doesnt deliver enough cobalamin to make a felt difference

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It transports long-chain fatty acids into the mitochondria so they can be oxidized or burned to produce energy

In aged rat models, oral 5-amino-1mq capsules significantly improved myocardial mitochondrial function, reduced cardiomyocyte apoptosis, decreased myocardial injury markers (such as CK-MB, cTnI), enhanced cardiac contractility, and alleviated aging-related myocardial fibrosis