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Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus

Conclusions Our results indicate that the preservation of -cell function by exenatide treatment may be mediated by alleviating both systemic inflammation via restoration of peripheral Th17/Treg balance and islet inflammation through inhibiting intra-islet infiltration of Th17 cells

None of these routes are approved for clinical or therapeutic use in humans, and all remain experimental

[18] Palmitoylation of delta catenin seems to coordinate activity-dependent changes in synaptic adhesion molecules, synapse structure, and receptor localizations that are involved in memory formation