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Other matrix metalloproteinases-related developments in osteoarthritis Matrix metalloproteinases-generated neoepitope of C-reactive protein a potential osteoarthritis biomarker A study from 2021 demonstrated the capability of the MMP-generated neoepitope of C-reactive protein (CRPM) to be a biomarker of local and systemic inflammation in knee OA [57]

The study was conducted in strict accordance with institutional ethical guidelines and was approved by the Ethics Committee of Human and Animal Experiments at Rasht Branch, Islamic Azad University, Rasht, Iran (IR.IAU.RASHT.REC.1400.015)

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Molecular and therapeutic insights of Alpha-Lipoic acid as a potential molecule for disease prevention