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Timeline of Results with Tirzepatide: During the first month, most women notice appetite changes food cravings diminish portion sizes naturally decrease the constant thoughts about food start to quiet the scale begins moving, typically 3-8 pounds in the first few weeks By months 2-3, the changes become more visible

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In animals, SGLT2 inhibitors cause dilatation of the renal pelvis and tubules of the kidney when used during the second and third trimester and additionally a relatively large number of unfavorable human pregnancy outcomes are found in humans