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Orders over 92,000 ship free anywhere in Costa Rica, and ordering five or more vials of the same size triggers an automatic 15% bulk discount, bringing the 100mg vial down to 39,100 (3,910.00 per mg) and the 50mg vial down to 31,280

Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

Russian preclinical literature describes 25-100 mcg per administration, subcutaneous or intranasal, prior to sleep

Initial Storage Upon arrival, keep the lyophilized vials stored in a temperature-controlled environment