It included 338 adults with overweight or obesity (without diabetes) over 68 weeks
Functional enrichment analysis indicated these intersecting genes are primarily involved in biological processes including oxidative stress responses, smooth muscle cell proliferation, and reactive oxygen species (ROS) responses, closely matching RA pathological features such as excessive inflammatory factor release and oxidative stress injury ( We further applied three classical machine learning algorithms (LASSO, RFE-RF, and SVM) to cross-validate and identify two core genes, GPX3 and MYC, which were subsequently validated using an MLP model
However, eIF2 only inhibits the majority of the protein translation process while promoting the synthesis of transcription factor 4 (ATF4) (65, 66)
While some individuals report significant weight loss, results are not guaranteed, and the timeline above represents patterns, not promises