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For comparisons among three or more independent groups, one-way analysis of variance (ANOVA) followed by Tukeys multiple comparisons test was applied when variances were equal, whereas Welchs ANOVA with Dunnetts T3 post-hoc test was used when variances were unequal

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Endotoxin testing via LAL: Every batch is tested for bacterial endotoxins using the Limulus Amebocyte Lysate test per USP Chapter 85

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While extensive animal studies exist, human data is extremely limited and lacks rigorous clinical trials

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Both contain the same active ingredient, but precision dosing and supportive care make the PlexusDx approach gentler during the adjustment phase

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