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These medications may be acting on the knee through three simultaneous routes: reducing mechanical stress, protecting joint tissue directly and alleviating the pain that drives surgical decision-making. F&B takeaway: Whats important here is the ripple effect, says Circanas Lyons Wyatt

These drugs arent going to solve the problem, but they have a huge amount of promise. What else weve been reading As the debate over assisted dying in the UK shifts towards a majority view that the ban is an immoral anachronism, its really worth reading Anna Moores interview with the actor Liz Carr, whos made a BBC documentary that presents an alternative argument through the prism of her own disability

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