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More recent semaglutide data suggest improvements in sperm morphology and testosterone while preserving normal gonadotropin signaling. Philip Werthman, MD One of the most important clinical distinctions is that GLP-1 therapies appear fundamentally different from testosterone replacement therapy for men who wish to preserve fertility, he noted

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La mayor parte de la evidencia publicada proviene de modelos animales (rata, ratn) y estudios in vitro

b , GGT activity in untreated C57BL/6 mouse tissues (kidney, spleen, and liver