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In diabetes studies, about 4 to 7 out of 10 people experience some stomach problems, but most are mild

Future trials should stratify patients by metabolic phenotype, incorporate mechanistic biomarkers, and include long-term follow-up to evaluate both psychiatric and metabolic endpoints

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Botana M, Escalada J, Merchante , Reyes R, Rozas P (2022) Prevention of cardiorenal complications with sodiumglucose cotransporter type 2 inhibitors: a narrative review