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However, understanding which symptoms are expected and which warrant medical attention is essential for patient safety

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The failures in many antioxidant clinical trials likely arise from starting the therapies in the late stages of AD, not monitoring drug levels and markers for the in vivo therapeutic effect of the drug, not utilizing a multi-antioxidant approach that covers both lipophilic and hydrophilic areas of the cell or recycle the oxidized antioxidants back to the reduced state, and not taking into account the basal redox status of the subjects in the trials [10

Although these two groups operate in the context of medicine, there is considerable overlap with sedation/anaesthesia for dentistry