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These sensory nerves are involved in protecting the gastric mucosa from various stimuli, and CGRP acts as potential mediator in this process, increasing gastric mucosal blood flow, inhibiting gastric acid secretion, and preventing apoptosis and oxidative damage 354

Attempts have been made to study the effects of TMAO on cardiac muscle at the molecular level

doi: 10.3389/fnagi.2020.588044 Received 28 July 2020 Accepted 23 October 2020 Published 24 November 2020 Volume 12 - 2020 Edited by George Tetz, Human Microbiology Institute, United States Reviewed by Vanessa Castelli, University of L'Aquila, Italy

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