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Weight loss, regardless of the method achieved, can significantly impact menstrual regularity through multiple physiological pathways

Brookmeyer R, Corrada MM, Curriero FC, Kawas C

In general, these hypotheses present the assumption that microbiota of proper composition regulates epithelial barrier function, including by regulating barrier permeability and TJ, influencing vascular permeability and angiogenesis, and affecting local inflammation and GALT tolerance [1, 55, 56]