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While LF is generally well-tolerated, some side effects such as temporary fecal loosening have been noted, particularly with oral administration, necessitating careful monitoring during extended use ( 4.3 Probiotics 4.3.1 Definitions, biological functions, and areas of application Probiotics are live microorganisms that offer health benefits

Under normal conditions, MMP activity is tightly regulated to maintain tissue homeostasis

In vitro studies demonstrated that treatment with liraglutide or exendin-4 significantly attenuated oxidative stress and cellular apoptosis in SH-SY5Y cells exposed to methylglyoxal or high glucose, which mimicked the pathophysiological conditions of diabetic neuropathy [79, 80]