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If your GLP-1 pen is refrigerated, you may remove it approximately 30 minutes before injection to allow it to reach room temperature (following your specific product's storage guidelines), as cold medication can cause discomfort

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With clinical trials ongoing, phase 3 results arrive in 2026, guiding future treatment guidelines and potentially FDA approval

Coffee enema with PEG group A split dose of PEG (1 L of the total 2-L dose) was administered before and after the coffee enema