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GLP-1 medications also arent recommended if youre pregnant, planning to become pregnant, or breastfeeding

A flow diagram of data collection and analysis of tirzepatide-associated adverse events from the FAERS database is shown in Fig

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Consistently feeling sad, empty, and hopeless Markedly diminished interest in pleasurable activities Significant weight loss or weight gain Increased or decreased appetite Insomnia or hypersomnia Fatigue or loss of energy Feeling of worthlessness, feeling excessive, or inappropriate guilt Diminished ability to think or concentrate, or indecisiveness Recurrent thoughts of death and suicidal ideation without a specific plan Psychomotor agitation or retardation These symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning