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Although direct evidence linking these effects to gut microbiota metrics remains limited, the overlapping mechanistic networks strongly suggest that TCM bioactive compounds may achieve their multi-target therapeutic effects through remodeling gut microbial ecosystems
In addition, the accumulation of acylcarnitine in the pathological state of the liver leads to insulin resistance, which further aggravates the development of liver diseases and results in a vicious cycle [211]
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The structural conservation of the I site suggests that this protomer glue is widely used, with natural molecules remaining associated at this site for many purified enteroviruses
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