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On the other hand, it was shown in a colon cancer model that CD36, by favoring the uptake of PA, directly promotes the sensitivity of the cancer cells themselves to ferroptosis [32]

First-line inavolisib/placebo + palbociclib + fulvestrant (Inavo/Pbo+Palbo+Fulv) in patients (pts) with PIK3CA-mutated, hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer who relapsed during/within 12 months (mo) of adjuvant therapy