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CoQ10, melatonin, DHEA (if indicated for low ovarian reserve), omega-3s, and comprehensive antioxidant support are all reasonable additions to a preconception regimen, in addition to medical evaluation and potentially assisted reproductive technology

[3] [4] These medications work by mimicking the incretin hormone glucagon-like peptide-1, which enhances insulin secretion, suppresses glucagon release, and significantly reduces appetite primarily through central satiety pathways, with some slowing of gastric emptying (an effect that may attenuate over time)

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Am J Physiol Cell Physiol 308(9):C729C736