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PAR2 is activated by several soluble trypsin-like proteases and multiple transmembrane-anchored serine proteases (TMPRSSs) (3335), but their roles in PAR2-mediated metabolic control are incompletely understood

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In 2016, the International Agency for Research on Cancer identified 13 obesity-associated cancers (OACs) with increased incidence and poorer prognosis among people with excess body weight

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