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2011 Sep-Oct;23(5):220-6 2

SIRT3-mediated deacetylation of IDH2 increases the generation of mitochondrial NADPH, which elevates the reduced GSH levels

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According to the pH range, CHE exists in two forms, charged iminium in the pH range 16 and alkanolamine form in the pH range 8.511, which transform into each other in an equilibrium reaction and have extensive biological and biochemical performance in vivo