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Gallbladder disease : GLP-1 receptor agonists may increase the risk of gallstones (cholelithiasis) and gallbladder inflammation (cholecystitis)
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In its standing guidance on unapproved GLP-1 drugs, the US FDA warned companies that have illegally sold unapproved drugs containing semaglutide, tirzepatide or retatrutide that are falsely labeled for research purposes or not for human consumption. The agency was specific that these products have been sold directly to consumers for human use with dosing instructions, which is to say the FDA understands perfectly well that the research only label is a fig leaf and has said so
A 20 mg tirzepatide vial with 1 mL of bacteriostatic water makes 20 mg/mL, where 10 mg draws 50 units and 15 mg draws 75 units
